British Thoracic Society guideline for advanced diagnostic and therapeutic flexible bronchoscopy in adults.

Conventional transbronchial fine needle aspiration (TBNA) B < Conventional transbronchial needle aspiration (TBNA) is a safe technique and should be used to sample mediastinal and hilar lymphadenopathy during initial diagnostic bronchoscopy where a pre-procedure CT scan has demonstrated significant adenopathy. < Conventional TBNA is a safe technique for sampling hilar and mediastinal lymph nodes in cases of suspected sarcoidosis and may be used in conjunction with endobronchial and transbronchial biopsies. O < Depending upon the clinical setting, a non-diagnostic conventional TBNA result may warrant further investigation. Real-time endobronchial ultrasound-guided TBNA (EBUS-TBNA) or surgical lymph node sampling should be considered. Endobronchial ultrasound-guided transbronchial fine needle aspiration (EBUS-TBNA) B < EBUS-TBNA is a safe and effective technique for the assessment of hilar and mediastinal lymph nodes in cases of confirmed or suspected lung cancer. < EBUS-TBNA is a safe and effective technique for sampling hilar and mediastinal lymph nodes in cases of suspected sarcoidosis and may be used in conjunction with endobronchial and transbronchial biopsies. D < EBUS-TBNA is a safe and effective technique for sampling paratracheal and peribronchial intraparenchymal lung masses. < At present there is insufficient evidence to recommend EBUS-TBNA for routine use in the diagnosis of lymphoma. O < In cases where EBUS-TBNA results are negative for malignancy, a confirmatory surgical biopsy should be performed where appropriate. Therapeutic procedures for malignant disease